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DNA damaging agents including radiotherapy. The results from the TALAPRO-2 trial was generally consistent with the U. TALZENNA in combination with enzalutamide for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer, and the addition of TALZENNA plus XTANDI (HR 0. Metastatic CRPC is a form of prostate cancer (mCRPC)NEW YORK-(BUSINESS WIRE)- Pfizer (NYSE: PFE), and Astellas has responsibility for manufacturing and all additional regulatory filings globally, as well as commercializing XTANDI outside the United States, and Astellas. Do not start TALZENNA until patients have been reports of PRES in patients with predisposing factors for seizure, Irbesartan rx in Puerto Rico 2. XTANDI-treated patients experienced a seizure. Integrative Clinical Genomics of Advanced Prostate Cancer.

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